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Thymol-d<sub>13</sub>

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2465

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9

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6

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1

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7

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10

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2403

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N6810S
    Thymol-d13

    		Bacterial
    Thymol-d13 is the deuterium labeled Thymol[1]. Thymol is the main monoterpene phenol occurring in essential oils isolated from plants belonging to the Lamiaceae family, and other plants such as those belonging to the Verbenaceae, Scrophulariaceae, Ranunculaceae and Apiaceae families. Thymol has antioxidant, anti-inflammatory, antibacterial and antifungal effects[2].
    <em>Thymol-d</em><em>13</em>
  • HY-D0184S4
    2'-Deoxycytidine-d13

    Deoxycytidine-d<sub>13sub>; Cytosine deoxyriboside-d<sub>13sub>; Deoxyribose cytidine-d<sub>13sub>

    		 Isotope-Labeled Compounds Endogenous Metabolite Others
    2'-Deoxycytidine-d13 (Deoxycytidine-d13; Cytosine deoxyriboside-d13; Deoxyribose cytidine-d13) is deuterium labeled 2'-Deoxycytidine (HY-D0184). 2'-Deoxycytidine, a deoxyribonucleoside, could inhibit biological effects of Bromodeoxyuridine (Brdu).
    2'-Deoxycytidine-d<em>13</em>
  • HY-N0097S5
    Guanosine-d13

    DL-Guanosine-d<sub>13sub>; Vernine-d<sub>13sub>

    		 Isotope-Labeled Compounds Infection
    Guanosine-d13 (DL-Guanosine-d13) is a deuterium of Guanosine (HY-N0097). Guanosine (DL-Guanosine) is a purine nucleoside comprising guanine attached to a ribose (ribofuranose) ring via a β-N9-glycosidic bond. Guanosine possesses anti-HSV activity .
    Guanosine-d<em>13</em>
  • HY-17563S3
    2'-Deoxyguanosine-d13

    Deoxyguanosine-d<sub>13sub>; Guanine deoxyriboside-d<sub>13sub>

    		 Isotope-Labeled Compounds Endogenous Metabolite Cancer
    2'-Deoxyguanosine-d13 (Deoxyguanosine-d13; Guanine deoxyriboside-d13) is deuterium labeled 2'-Deoxyguanosine (HY-17563). 2'-Deoxyguanosine (Deoxyguanosine) is deoxyguanosine.
    2'-Deoxyguanosine-d<em>13</em>
  • HY-B0228S12
    Adenosine-d13

    Adenine riboside-d<sub>13sub>; D-Adenosine-d<sub>13sub>

    		 Isotope-Labeled Compounds Nucleoside Antimetabolite/Analog Endogenous Metabolite Autophagy Apoptosis Metabolic Disease Cancer
    Adenosine-d13 (Adenine riboside-d13; D-Adenosine-d13) is deuterium labeled Adenosine (HY-B0228). Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physiology, including neuronal activity, vascular function, platelet aggregation, and blood cell regulation.
    Adenosine-d<em>13</em>
  • HY-RS13999
    SUB1 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    SUB1 Human Pre-designed siRNA Set A contains three designed siRNAs for SUB1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    SUB1 Human Pre-designed siRNA Set A
    SUB1 Human Pre-designed siRNA Set A
  • HY-146227
    DNA topoisomerase II inhibitor 1

    		Topoisomerase Apoptosis Cancer
    DNA topoisomerase II inhibitor 1 (compound 8ed) is a potent DNA topoisomerase II inhibitor. DNA topoisomerase II inhibitor 1 shows anti-proliferative activity. DNA topoisomerase II inhibitor 1 induces apoptosis and cell cycle arrest at sub G1 phase .
    DNA topoisomerase II inhibitor 1
  • HY-107372S3
    Uridine triphosphate-d13 dilithium

    UTP-d<sub>13sub> dilithium; Uridine 5'-triphosphate-d<sub>13sub> dilithium

    		 Isotope-Labeled Compounds Endogenous Metabolite DNA/RNA Synthesis Cardiovascular Disease Inflammation/Immunology Cancer
    Uridine triphosphate-d13 (UTP-d13 dilithium; Uridine 5'-triphosphate-d13) dilithium is deuterium labeled Uridine triphosphate (HY-107372). Uridine triphosphate (UTP;Uridine 5'-triphosphate) is a nucleotide that regulates the functions of the pancreas in endocrine and exocrine secretion, proliferation, channels, transporters, and intracellular signaling under normal and disease states.
    Uridine triphosphate-d<em>13</em> dilithium
  • HY-N0055S
    Chlorogenic acid-13C3

    3-O-Caffeoylquinic acid-<sub>13sub>C3; Heriguard-<sub>13sub>C3; NSC-407296-<sub>13sub>C3

    		 Isotope-Labeled Compounds Cancer
    Chlorogenic acid- 13C3 (Heriguard- 13C3; NSC-407296- 13C3) is 13C- and 15N-labeled Chlorogenic acid (HY-N0055). Chlorogenic acid is a major phenolic compound in Lonicera japonica Thunb.. It plays several important and therapeutic roles such as antioxidant activity, antibacterial, hepatoprotective, cardioprotective, anti-inflammatory, antipyretic, neuroprotective, anti-obesity, antiviral, anti-microbial, anti-hypertension .
    Chlorogenic acid-<em>13</em>C3
  • HY-B0158S8
    Cytidine-d13

    Cytosine β-D-riboside-d<sub>13sub>; Cytosine-1-β-D-ribofuranoside-d<sub>13sub>

    		 Nucleoside Antimetabolite/Analog Endogenous Metabolite Isotope-Labeled Compounds Neurological Disease
    Cytidine-d13 (Cytosine β-D-riboside-d13; Cytosine-1-β-D-ribofuranoside-d13) is deuterium labeled Cytidine (HY-B0158). Cytidine is a pyrimidine nucleoside and acts as a component of RNA. Cytidine is a precursor of uridine. Cytidine controls neuronal-glial glutamate cycling, affecting cerebral phospholipid metabolism, catecholamine synthesis, and mitochondrial function .
    Cytidine-d<em>13</em>
  • HY-19883S
    Lusutrombopag-d13

    S-888711-d<sub>13sub>

    		 Isotope-Labeled Compounds Thrombopoietin Receptor Inflammation/Immunology
    Lusutrombopag-d13 is deuterium labeled Lusutrombopag. Lusutrombopag is an orally bioavailable thrombopoietin (TPO) receptor agonist, used for treatment of chronic liver disease.
    Lusutrombopag-d<em>13</em>
  • HY-B0282AS2
    Acetylcholine-d13 bromide

    ACh-d<sub>13sub> bromide

    		 nAChR Calcium Channel Endogenous Metabolite Isotope-Labeled Compounds Others
    Acetylcholine-d13 (bromide) is the deuterium labeled Acetylcholine bromide[1].
    Acetylcholine-d<em>13</em> bromide
  • HY-109506S5
    DPPC-d13

    129Y83-d<sub>13sub>

    		 Isotope-Labeled Compounds Endogenous Metabolite Others
    DPPC-d13 is deuterium labeled DPPC. DPPC (129Y83) is a zwitterionic phosphoglyceride that can be used for the preparation of liposomal monolayers. DPPC-liposome serves effectively as a delivery vehicle for inducing immune responses against GSL antigen in
    DPPC-d<em>13</em>
  • HY-W040193S6
    1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d13

    1,2-Distearoyl-sn-glycero-3-PC-d<sub>13sub>; DSPC-d<sub>13sub>

    		 Isotope-Labeled Compounds Liposome Others
    1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d13 is deuterium labeled 1,2-Distearoyl-sn-glycero-3-phosphorylcholine. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine (1,2-Distearoyl-sn-glycero-3-PC; DSPC) is a cylindrical-shaped lipid. 1,2-Distearoyl-sn-gly
    1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d<em>13</em>
  • HY-129240S
    13-cis Acitretin-d3

    Isoacitretin d<sub>3sub>; Ro 13-7652 d<sub>3sub>

    		 Drug Metabolite Inflammation/Immunology
    13-cis Acitretin-d3 is a deuterium labeled 13-cis Acitretin. 13-cis Acitretin is the metabolite of Acitretin after chronic administration. Acitretin(Ro 10-1670) is a second-generation, systemic retinoid that has been used in the treatment of psoriasis[1][2].
    <em>13</em>-cis Acitretin-d3
  • HY-I0357S
    Hexyl chlorocarbonate-d13

    Hexyl chloroformate-d<sub>13sub>; Hexyloxycarbonyl-d13 chloride

    		 Isotope-Labeled Compounds Others
    Hexyl chlorocarbonate-d13 is the deuterium labeled Hexyl chlorocarbonate[1].
    Hexyl chlorocarbonate-d<em>13</em>
  • HY-W392933S5
    Thymidine 5'-monophosphate-d13 dilithium

    Thymidine-5'-phosphate-d<sub>13sub> dilithium

    		 Isotope-Labeled Compounds Others
    Thymidine 5'-monophosphate-d13 (Thymidine-5'-phosphate-d13) dilithium is deuterium labeled Thymidine 5'-monophosphate (HY-W392933).
    Thymidine 5'-monophosphate-d<em>13</em> dilithium
  • HY-109541S3
    1,2-Dimyristoyl-sn-glycero-3-phosphocholine-d13

    DMPC-d<sub>13sub>

    		 Liposome Isotope-Labeled Compounds Others
    1,2-Dimyristoyl-sn-glycero-3-phosphocholine-d13 is deuterium labeled 1,2-Dimyristoyl-sn-glycero-3-phosphocholine. 1,2-Dimyristoyl-sn-glycero-3-phosphocholine (DMPC) is a synthetic phospholipid used in liposomes. 1,2-Dimyristoyl-sn-glycero-3-phosphocholine
    1,2-Dimyristoyl-sn-glycero-3-phosphocholine-d<em>13</em>
  • HY-N6746S1
    Citrinin-13C13

    NSC 186-13C<sub>13

    		 Isotope-Labeled Compounds Cancer
    Citrinin- 13C13 (NSC 186- 13C13) is the 13C labeled Citrinin (HY-N6746) . Citrinin is a mycotoxin which causes contamination in the food and is associated with different toxic effects. Citrinin is usually found together with another nephrotoxic mycotoxin, Ochratoxin A. Citrinin is also reported to possess a broad spectrum of bioactivities, including antibacterial, antifungal, and potential anticancer and neuro-protective effects in vitro .
    Citrinin-<em>13</em>C<em>13</em>
  • HY-W392933S1
    Thymidine 5'-monophosphate-15N2,d13 dilithium

    Thymidine-5'-phosphate-15N<sub>2sub>,d<sub>13sub> dilithium

    		 Isotope-Labeled Compounds Others
    Thymidine 5'-monophosphate- 15N2,d13 (Thymidine-5'-phosphate- 15N2,d13) dilithium is deuterium and 15N labeled Thymidine 5'-monophosphate (HY-W392933).
    Thymidine 5'-monophosphate-15N2,d<em>13</em> dilithium
  • HY-125833
    Alpha-Naphthoflavone
    5 Publications Verification

    		 Cytochrome P450 Aryl Hydrocarbon Receptor Apoptosis Cancer
    Alpha-Naphthoflavone is an orally active flavonoid that is a potent, competitive inhibitor of aromatase< b>aromatase. < b > IC < sub > 50 < / sub > < / b > and < b > K < sub > I < / sub > < / b > value were 0.5 and 0.2 microns. Alpha-Naphthoflavone can inhibit cell proliferation and induce apoptosis .
    Alpha-Naphthoflavone
  • HY-157440
    AChE/Aβ-IN-3

    		Amyloid-β Reactive Oxygen Species Cholinesterase (ChE) Neurological Disease
    AChE/Aβ-IN-3 (compound AM5) is a dual inhibitor of AChE and Amyloid-β aggregation with IC50<.sub> values of 1.29 and 4.93 μM, respectively. AChE/Aβ-IN-3 has antioxidant properties that scavenge ROS and restore their normal levels. AChE/Aβ-IN-3 can be used in the study of neurological diseases, such as Alzheimer's disease .
    AChE/Aβ-IN-3
  • HY-144290
    ARN25068

    		GSK-3 DYRK Neurological Disease
    ARN25068 is a sub-micromolar inhibitor of the three protein kinases, GSK-3β, FYN and DYRK1A to tackle tau hyperphosphorylation .
    ARN25068
  • HY-N7118
    Clindamycin hydrochloride monohydrate

    		Bacterial Antibiotic Infection Cancer
    Clindamycin hydrochloride monohydrate is an oral protein synthesis inhibitory agent that has the ability to suppress the expression of virulence factors in Staphylococcus aureus at sub-inhibitory concentrations (sub-MICs). Clindamycin hydrochloride monohydrate resistance results from enzymatic methylation of the antibiotic binding site in the 50S ribosomal subunit (23S rRNA). Clindamycin hydrochloride monohydrate decreases the production of Panton-Valentine leucocidin (PVL), toxic-shock-staphylococcal toxin (TSST-1) or alpha-haemolysin (Hla) .
    Clindamycin hydrochloride monohydrate
  • HY-129946
    Dopamine D2 receptor antagonist-1

    		Dopamine Receptor Neurological Disease
    Dopamine D2 receptor antagonist-1 is a negative allosteric modulator (NAM) of the dopamine D2 receptor (D2R) with sub-mM affinity .
    Dopamine D2 receptor antagonist-1
  • HY-163129
    BPU

    		Apoptosis MMP Cancer
    BPU arrests cell cycle progression in the sub-G1 phase. BPU is an anticancer agent through inhibiting blood vessel formation in tumor tissues .
    BPU
  • HY-139823A
    PRMT5-IN-11

    		Histone Methyltransferase Others
    PRMT5-IN-11 is a promising structure-dependent inhibition of the protein methyltransferase PRMT5:MEP50 complex in the (sub)micromolar range.
    PRMT5-IN-11
  • HY-144220
    NLRP3/AIM2-IN-1

    		NOD-like Receptor (NLR) Inflammation/Immunology
    NLRP3/AIM2-IN-1 is a thermal sepsis inhibitor with an < b > IC < sub > 50 < / sub > < / b > value of 3.136 ± 0.7667 μ M.
    NLRP3/AIM2-IN-1
  • HY-N11799
    Neochilenin

    3-O-Methylquercetin 4′-O-glucoside

    		 Others Others
    Neochilenin (3-O-Methylquercetin 4 '-O-glucoside) is a glycoside of 3-O-methylquercetin, which can be isolated from the sub-family Cereoideae (Cactaceae). .
    Neochilenin
  • HY-157728
    ML307

    		E1/E2/E3 Enzyme Inflammation/Immunology
    ML307 is a potent, sub-micromolar, first-in-class Ubc13 enzyme activity inhibitor with an IC50 of 781 nM. ML307 has the potential for immunomodulation and inflammation research .
    ML307
  • HY-111258
    GSK345931A

    		Prostaglandin Receptor Neurological Disease Inflammation/Immunology
    GSK345931A is an EP1 receptor antagonist. GSK345931A shows measurable CNS penetration in the mouse and rat and potent analgesic efficacy in acute and sub-chronic models of inflammatory pain .
    GSK345931A
  • HY-P3426
    BACE1-IN-10

    		Beta-secretase Cancer
    BACE1-IN-10 is a potent BACE1 Inhibitor. BACE1-IN-10 shows sub-micromolar activity against recombinant BACE1 (rBACE1) .
    BACE1-IN-10
  • HY-P5856
    αA-Conotoxin PIVA

    		nAChR Neurological Disease
    αA-Conotoxin PIVA is a selective mouse musclenAChR inhibitor with IC50 for adult and fetal mouse musclenAChR sub> values are 2.3 nM and 22 nM respectively. αA-Conotoxin PIVA can be used in the study of neurological diseases.
    αA-Conotoxin PIVA
  • HY-B1455
    Clindamycin
    5 Publications Verification
    Clindamycin is an orally active and broad-spectrum bacteriostatic lincosamide antibiotic. Clindamycin can inhibit bacterial protein synthesis, possessing the ability to suppress the expression of virulence factors in Staphylococcus aureus at sub-inhibitory concentrations (sub-MICs). Clindamycin resistance results from enzymatic methylation of the antibiotic binding site in the 50S ribosomal subunit (23S rRNA). Clindamycin decreases the production of Panton-Valentine leucocidin (PVL), toxic-shock-staphylococcal toxin (TSST-1) or alpha-haemolysin (Hla). Clindamycin also can be used for researching malaria .
    Clindamycin
  • HY-111673
    8-CPT-Cyclic AMP sodium

    8-CPT-cAMP sodium; 8-(p-Chlorophenylthio)-cAMP sodium

    		 PKA Phosphodiesterase (PDE) Inflammation/Immunology
    8-CPT-Cyclic AMP (8-CPT-cAMP) sodium is a selective activator of cyclic AMP-dependent protein kinase (PKA). 8-CPT-Cyclic AMP sodium is also a potent inhibitor of the cyclic GMP-specific phosphodiesterase (PDE VA) with an IC50 of 0.9 μM. 8-CPT-Cyclic AMP sodium also inhibits PDE III and PDE IV with IC50 s of 24 and 25 μM, respectively. 8-CPT-Cyclic AMP sodium is a very high affinity for Epac and is a potent Epac activator .
    8-CPT-Cyclic AMP sodium
  • HY-U00037
    Ecopladib

    PLA 725

    		 Phospholipase Inflammation/Immunology
    Ecopladib is a sub-micromolar inhibitor of cytosolic phospholipase A2α (cPLA2α), with IC50s of 0.15 μM and 0.11 μM in the GLU micelle and rat whole blood assays, respectively.
    Ecopladib
  • HY-111192
    IPR-803
    1 Publications Verification

    		 Ser/Thr Protease Cancer
    IPR-803 is a potent inhibitor of the uPAR•uPA protein-protein interaction (PPI). IPR-803 binds directly to uPAR with sub-micromolar affinity. IPR-803 displays anti-tumor activity .
    IPR-803
  • HY-144238
    mPGES1-IN-6

    		PGE synthase Inflammation/Immunology
    MPGES-1 is considered as a promising therapeutic target of the next generation anti-inflammatory drugs in the research of inflammatory diseases. The < b > IC < sub > 50 < / sub > < / b > value of mPGES1-IN-6 is 0.03 μ M。
    mPGES1-IN-6
  • HY-W102714
    1,2-Cyclohexylenedinitrilotetraacetic acid

    CDTA

    		 Others Metabolic Disease
    1,2-Cyclohexylenedinitrilotetraacetic acid (CDTA) is a chelating agent. 1,2-Cyclohexylenedinitrilotetraacetic acid has an ability to remove manganese from brain and liver (in vivo) and their sub-cellular fractions (in vitro), of rats pretreated with manganese sulphate .
    1,2-Cyclohexylenedinitrilotetraacetic acid
  • HY-144232
    Anticancer agent 28

    		Others Cancer
    Anticancer agent 28 showed good antitumor activity in H22 allogeneic mice in vivo. Its potency in K562 cells was 50 times that of oridonin, and its < b > IC < sub > 50 < / sub > < / b > value was 0.09 μ M。
    Anticancer agent 28
  • HY-W011474
    Geranylgeraniol

    		NF-κB Inflammation/Immunology
    Geranylgeraniol is an orally acitve vitamin K2 sub-type, an intermediate of the mevalonate pathway. Geranylgeraniol targets NF-kB signaling pathway and could alleviate LPS-induced microglial inflammation in animal model .
    Geranylgeraniol
  • HY-18961
    PD 407824

    PD 407824 is a checkpoint kinase Chk1 and WEE1 inhibitor with IC50s of 47 and 97 nM, respectively. PD 407824 is a chemical BMP sensitizer and increases the sensitivity of cells to sub-threshold amounts of BMP4 .
    PD 407824
  • HY-118423
    SJ-3366

    IQP-0410

    		 HIV Inflammation/Immunology
    SJ-3366 (IQP-0410) is a potent inhibitor of HIV nonnucleoside reverse transcriptase . SJ-3366 (IQP-0410) inhibits HIV at sub-nanomolar concentrations primarily through a typical non-nucleoside mechanism .
    SJ-3366
  • HY-147781
    Anticancer agent 66

    		Apoptosis Cancer
    Anticancer agent 66 (Compound 13e) is an anti-cancer agent. Anticancer agent 66 induces apoptosis and increases sub-G1 cell population in MCF-7 cells. Anticancer agent 66 is a ciprofloxacin analog .
    Anticancer agent 66
  • HY-147782
    Anticancer agent 67

    		Apoptosis Cancer
    Anticancer agent 67 (Compound 13g) is an anti-cancer agent. Anticancer agent 67 induces apoptosis and increases sub-G1 cell population in MCF-7 cells. Anticancer agent 67 is a ciprofloxacin analog .
    Anticancer agent 67
  • HY-B1455S
    Clindamycin-d3 hydrochloride

    		Bacterial Antibiotic Parasite Infection
    Clindamycin-d3 (hydrochloride) is the deuterium labeled Clindamycin. Clindamycin is an orally active and broad-spectrum bacteriostatic lincosamide antibiotic. Clindamycin can inhibit bacterial protein synthesis, possessing the ability to suppress the expression of virulence factors in Staphylococcus aureus at sub-inhibitory concentrations (sub-MICs). Clindamycin resistance results from enzymatic methylation of the antibiotic binding site in the 50S ribosomal subunit (23S rRNA). Clindamycin decreases the production of Panton-Valentine leucocidin (PVL), toxic-shock-staphylococcal toxin (TSST-1) or alpha-haemolysin (Hla). Clindamycin also can be used for researching malaria[1][2].
    Clindamycin-d3 hydrochloride
  • HY-135845
    TP3011

    CH0793011

    		 Topoisomerase Cancer
    TP3011 (CH0793011) is an active metabolite of CH-0793076 and is a potent topoisomerase I inhibitor equipotent as SN38 . TP3011 is against cancer cell lines growth with IC50s at the range sub-nanomolar in vitro .
    TP3011
  • HY-149033
    Kobusine derivative-2

    		Others Cancer
    Kobusine derivative-2, a kobusine derivative, has antiproliferative activity against cancer cells. Kobusine derivative-2 can induce the arrest of MDA-MB-231 cells in the sub-G1 phase. Anticancer activity .
    Kobusine derivative-2
  • HY-103235
    NPEC-caged-(S)-AMPA

    		iGluR Neurological Disease
    NPEC- caged-(S)-AMPA, a caged neurotransmitter analog, is a NPEC photoprotecting group caged the (S)-AMPA (HY-100815A) to make caged ligands specific for glutamate receptor sub-types. NPEC- caged-(S)-AMPA selectively activates AMPA receptor .
    NPEC-caged-(S)-AMPA
  • HY-B1455S1
    Clindamycin-13C,d3

    		Isotope-Labeled Compounds Bacterial Antibiotic Parasite Infection
    Clindamycin- 13C,d3 is the 13C- and deuterium labeled Clindamycin. Clindamycin is an orally active and broad-spectrum bacteriostatic lincosamide antibiotic. Clindamycin can inhibit bacterial protein synthesis, possessing the ability to suppress the expression of virulence factors in Staphylococcus aureus at sub-inhibitory concentrations (sub-MICs). Clindamycin resistance results from enzymatic methylation of the antibiotic binding site in the 50S ribosomal subunit (23S rRNA). Clindamycin decreases the production of Panton-Valentine leucocidin (PVL), toxic-shock-staphylococcal toxin (TSST-1) or alpha-haemolysin (Hla). Clindamycin also can be used for researching malaria[1][2][3].
    Clindamycin-<em>13</em>C,d3

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